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Tropacocain HCl

Tropacocaine HCl properties

Synonym: NSC 76018
CAS-Nummer: 637-23-0
Formel: C 15 H 19 NEIN 2  • HCl
Molmasse: 281.8
Reinheit: >98%

Preisspanne: €36.95 bis €504.95

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Product Definition: Tropacocaine HCl (Research Chemical)

Chemischer Name:  Tropacocaine hydrochloride
Synonyme:  Tropacocaine HCl, Benzoylecgonine methyl ester
Molekularformel:  C₁₅H₁₉NO₂•HCl
Molekulargewicht:  281.78 g/mol
CAS No.:  537-26-8
Appearance:  White crystalline powder
Reinheit:  ≥98% (HPLC verified)
Löslichkeit:  50 mg/ml in water

Description & Pharmacology:
Tropacocaine is a naturally occurring cocaine analog with:
Local anesthetic effects
Stimulant properties
Shorter duration of action than cocaine (1-2 hours)
More selective noradrenaline reuptake inhibition

Research applications:

  1. Neuroscience research:

    • Dopamine transporter studies

    • Comparative pharmacology of stimulants

  2. Medical examination:

    • Local anesthetic mechanisms

    • Vasoconstriction studies

  3. Analytical chemistry:

    • Reference standard for drug analysis

    • Forensic investigation

Benefits for Research:
Naturally occurring compound
Less addiction potential than cocaine
Good stability in solution
Suitable for in vitro receptor studies

Risks & Limitations:
Possible side effects:

  • Tachycardia

  • Hypertension

  • CNS stimulation
    Limited pharmacokinetic data available
    Potential for abuse

Dosage protocol (for research):

AnwendungConcentrationExpected effect
In-vitro-Studien1-10 μMReceptor binding
Local anesthetic test0.1-0.5% solutionNerve block
Neurotransporter studies5-50 μMDopamine/noradrenaline effect

Safety measures:

  • Wear appropriate PPE (gloves, lab coat)

  • Work under a fume hood

  • Avoid contact with skin and eyes

  • Do not combine with MAO inhibitors

Frequently Asked Questions:

  1. Is Tropacocaine legal in the Netherlands?
    It may fall under the Opium Act as a cocaine-related substance.

  2. How is it different from cocaine?
    Less euphoric effect, shorter duration of action.

  3. Can it be used as a local anesthetic?
    For research purposes only, not for medical use.

  4. Is it detectable on drug tests?
    It may cross-react with cocaine tests.

Quality Control & Analytical Data:

Specifications:

  • Purity: ≥98% (HPLC)

  • Heavy metals: <1 ppm

  • Loss on drying: <0.5%

  • Residual solvents: <0.1%

Stabilitätsdaten:

  • Shelf life: 36 months at 15-25°C

  • Light sensitivity: Moderate

  • Moisture sensitivity: High

Conclusion:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.

⚠ For research purposes only – not for human use

Lagerungshinweis:

  • Airtight packaging

  • Store in a dark place

  • Dry at <25°C

Ethical considerations:

  • For use by qualified personnel only

  • Animal testing requires ethical approval

  • Document all experiments accurately

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