Tropacocain HCl
Tropacocaine HCl properties
Synonym: NSC 76018
CAS-Nummer: 637-23-0
Formel: C 15 H 19 NEIN 2 • HCl
Molmasse: 281.8
Reinheit: >98%
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Product Definition: Tropacocaine HCl (Research Chemical)
Chemischer Name: Tropacocaine hydrochloride
Synonyme: Tropacocaine HCl, Benzoylecgonine methyl ester
Molekularformel: C₁₅H₁₉NO₂•HCl
Molekulargewicht: 281.78 g/mol
CAS No.: 537-26-8
Appearance: White crystalline powder
Reinheit: ≥98% (HPLC verified)
Löslichkeit: 50 mg/ml in water
Description & Pharmacology:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition
Research applications:
Neuroscience research:
Dopamine transporter studies
Comparative pharmacology of stimulants
Medical examination:
Local anesthetic mechanisms
Vasoconstriction studies
Analytical chemistry:
Reference standard for drug analysis
Forensic investigation
Benefits for Research:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies
Risks & Limitations:
❌ Possible side effects:
Tachycardia
Hypertension
CNS stimulation
❌Limited pharmacokinetic data available
❌Potential for abuse
Dosage protocol (for research):
| Anwendung | Concentration | Expected effect |
|---|---|---|
| In-vitro-Studien | 1-10 μM | Receptor binding |
| Local anesthetic test | 0.1-0.5% solution | Nerve block |
| Neurotransporter studies | 5-50 μM | Dopamine/noradrenaline effect |
Safety measures:
Wear appropriate PPE (gloves, lab coat)
Work under a fume hood
Avoid contact with skin and eyes
Do not combine with MAO inhibitors
Frequently Asked Questions:
Is Tropacocaine legal in the Netherlands?
It may fall under the Opium Act as a cocaine-related substance.How is it different from cocaine?
Less euphoric effect, shorter duration of action.Can it be used as a local anesthetic?
For research purposes only, not for medical use.Is it detectable on drug tests?
It may cross-react with cocaine tests.
Quality Control & Analytical Data:
Specifications:
Purity: ≥98% (HPLC)
Heavy metals: <1 ppm
Loss on drying: <0.5%
Residual solvents: <0.1%
Stabilitätsdaten:
Shelf life: 36 months at 15-25°C
Light sensitivity: Moderate
Moisture sensitivity: High
Conclusion:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.
⚠ For research purposes only – not for human use
Lagerungshinweis:
Airtight packaging
Store in a dark place
Dry at <25°C
Ethical considerations:
For use by qualified personnel only
Animal testing requires ethical approval
Document all experiments accurately
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